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What are the signs of hypoxemia? Hypoxemia signs range depending on the severity and underlying trigger. Difficulty breathing or shortness of breath (dyspnea). Rapid coronary heart charge (tachycardia). Bluish color in skin, fingernails and lips (cyanosis). What is the most common cause of hypoxemia? Hypoxemia has many causes, but its most common cause is an underlying illness that impacts blood stream or respiratory (like heart or lung situations). Certain medications can slow respiration and lead to hypoxemia. Sleep apnea and mild lung disease could cause nocturnal hypoxemia - when your blood oxygen levels drop during your sleep. Being at high altitudes can also cause hypoxemia, which is why it can be arduous to breathe when you’re in the mountains. Acute respiratory distress syndrome (ARDS). Chronic obstructive pulmonary illness (COPD). Pneumothorax (air in the space round your lung or collapsed lung). Pulmonary edema (fluid on your lungs). Pulmonary embolism (blood clot in your lung).
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